دانلود مقاله ترجمه شده عفونت هم زمان آستروویروسی و روتاویروسی در کودکان مبتلا به گاستروآنتریت که به بیمارستان ابوذر اهواز واقع در جنوب ایران مراجعه کرده بودند

Abstract

Background: Acute gastroenteritis, which is one of the most common diseases in humans, is responsible for many illnesses in both children and adults. Group A rotaviruses are considered the main agents of gastroenteritis, and these are followed by calciviruses, adenoviruses, and astroviruses. Objectives: The aim of this study was to determine the rate of astrovirus and rotavirus coinfection among children up to 5 years of age who had gastroenteritis and who were referred to Ahvaz Aboozar Hospital. Patients  and  Methods:  A  total  of  180  stool  specimens,  which  were  collected  from  children with gastroenteritis who were less than 5 years old and who were referred to Ahvaz Aboozar Hospital, were tested by enzyme-linked immunosorbent assay methods for the detection of rotavirus infections. Detection of astroviruses in positive rotavirus stool specimens was performed by reverse transcriptase-polymerase chain reaction (RT-PCR) methods.Results:  Fifty-nine  of  the  180  samples  were  positive  for  rotavirus  infection.  These  positive samples were subjected to RT-PCR to test for astrovirus. After RT-PCR with specific astrovirus primer sets, 8 samples were positive for astrovirus as well. Therefore, 13% of rotavirus-positive samples were also positive for astrovirus. Conclusions: Group A rotaviruses, in addition to calciviruses, adenoviruses, and astroviruses,  can cause acute gastroenteritis. Studies have shown that 2.5 million deaths occur every year from gastroenteritis. In this study, we found that the prevalence of rotavirus infections was very high and that of coinfections of rotavirus and astrovirus were considerable. In order to reduce the risk of infections and to eliminate viral gastroenteritis in this zone of the region, education, vaccinations, and improved personal hygiene must be improved.