Abstract
Nowadays methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common multidrug resistant bacteria both in hospitals and in the community. In the last two decades, there has been growing concern about the increasing resistance to MRSA of the most potent antibiotic glycopeptides. MRSA infection poses a serious problem for physicians and their patients. Photosensitizer-mediated antimicrobial photodynamic therapy (PDT) appears to be a promising and innovative approach for treating multidrug resistant infection. In spite of encouraging reports of the use of antimicrobial PDT to inactivate MRSA in large in vitro studies, there are only few in vivo studies. Therefore, applying PDT in the clinic for MRSA infection is still a long way off
Contents
1. Introduction
2. Mechanisms of Antimicrobial PDT
3. Inactivating MRSA by PDT
4. Modification on Charge and Structure of Photosensitizers
5. New Drug Delivery Strategies Design
6. Targeted Antimicrobial PDT of MRSA
7. Microorganism Strain Selective and Antimicrobial PDT Resistant
8. Present Problems and Future Works
9. Conclusion
10. References